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Monitor Intently (1)elagolix will decrease the extent or result of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Metabolism Datopotamab deruxtecan-dlnk undergoes intracellular cleavage by lysosomal enzymes to launch DXd. The humanized Trop-two IgG1 monoclonal antibody is predicted to generally be degraded into modest peptides